No No little sisters must not hurt them. Be a big daddy, maybe an Elite rosie?

Off Note. Finished bioshock twice in a week, i felt horribal the first time through cause I killed all the LS's up to when 'Mother goose' saves you, then saw they were really just poor cute little girls, didn't kill any more. Second play through I saved all of them, got the good ending, and the achivement.